(521) The Impact of Donor Robotic Partial Hepatectomy on Sexual Function in Sexually Active Men: A Prospective Cohort Study

Abstract Introduction Donor robotic partial hepatectomy is evolving as a low morbidity method for liver transplantation. However, we have noticed that two of our patients complained de novo sexual dysfunction following their surgery. Factors may lead to the are and stress. Objective We set out objectively evaluate impact on function in sexually active men. Methods This prospective study involved cohort married men with no prior who consecutively presented donation from Jan 2021 Mar 2022. Robotic was performed using three ports Da Vinci XI system, small Pfannenstiel incision used deliver specimen. preoperative assessment IIEF-15 questionnaire [1], CLDQ-29 [2], perceived stress PSS-14 [3]. Lab investigations included hormonal profile, function, renal function. The postoperative repeated after months. Continuous data were compared paired t-test. References: 1. Rosen RC, et al (1997) Urology 49:822–830 2. Younossi ZM, (1999) Gut 45:295–300. 3. Cohen S, (1983) J Health Soc Behav. 24:385-96. Results Twenty-eight male donors, median age 31.5 SD 6.2 range 19-42 years, BMI 24.2 4.2 17.9-33.1 kg studied. At baseline, all had dysfunction, disease, or comorbidities. Preoperative morning testosterone 15.8 4.1 10.6-26.6 nmol/L. All normal hepatic Three months postoperatively, patient-reported dysfunction. There significant difference erectile domain pre postoperative, respectively (mean 27.2 5.3 27.7 5.4, p = 0.162). change desire, orgasmic, satisfaction domains. average score (6.9 0.33 6.9 0.33, p=0.378) its domains abdominal symptoms, fatigue, systemic activity, emotional worry. level before surgery, total scores 21.6 6.6 21.5 6.7, p=0.739, respectively. Conclusions In this cohort, did not find association between donor development involving larger number reveal more subtle changes underlying mechanisms. Disclosure No